The Center for Translational Cancer Research


(In Progress...) Have publications you would like to add to the list? please email them to Benjamin Rohe at



Gurski LA, Petrelli NJ, Jia X, and Farach-Carson MC.  Three-dimensional matrices for anti-cancer drug testing and development.  Oncology Issues 2010; 25:20-25 (Full Text PDF)

Li Y, Galileo DS Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion. Cancer Cell Int. 2010 Sep 15;10:34. (Full Text PDF)

Pradhan S, Liu C, Zhang C, Jia X, Farach-Carson MC and Witt RL.  Lumen formation in three-dimensional cultures of salivary acinar cells.  Otolaryngology - Head and Neck Surgery.  2010; 142:191-195 (Full Text PDF)

Pradhan S and Farach-Carson MC.  Mining the extracellular matrix for tissue engineering applications. Regenerative Medicine. 2010; 5(6): 961-970 (Full Text PDF)

Thompson WR, Modla S, Grindel BJ, Czymmek KJ, Wang L, Duncan RL, Farach-Carson MC. Perlecan/Hspg2 Deficiency Alters the Pericellular Space of the Lacuno-Canalicular System Surrounding Osteocytic Processes in Cortical Bone. Journal of Bone and Mineral Research. 2010 Sep 2. [Epub ahead of print] (Full Text PDF)

Wang X, Gurski LA, Zhong S, Xu X, Pochan DJ, Farach-Carson MC, Jia X.  Amphiphilic block copolyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin.  J Biomat Sci-Polym E 2010 in press.

Zhang C, Soori M, Miles FL, Sikes RA, Carson DD, Chung LW and Farach-Carson MC. Paracrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells. The Prostate. 2010. E-Publish ahead of print. (Full Text PDF)


Dharmaraj N, Gendler SJ, Carson DD. Expression of human MUC1 during early pregnancy in the human MUC1 transgenic mouse model. Biol Reprod. 2009. 81(6):1182-1188. (Full Text PDF)

Griffiths GS, Galileo DS, Aravindan RG, Martin-DeLeon PA. Clusterin facilitates exchange of glycosyl phosphatidylinositol-linked SPAM1 between reproductive luminal fluids and mouse and human sperm membranes. Biol Reprod. 2009. 81(3):562-70. (Full Text PDF)

Gurski LA, Jha AK, Zhang C, Jia X, and Farach-Carson MC.  Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells.  Biomaterials 2009; 30:6076-6085 (Full Text PDF)

Naik, MU, Nigam, A, Manrai, P, Millili, P, Czymmek, K, Sullivan, M and Naik, UP. CIB1 deficiency results in impaired thrombosis: the potential role of CIB1 in outside-in signaling through integrin αIIbβ3. J Thrombosis Haemostasis. 2009. 7: 1906–1914. (Full Text PDF)

Pradhan S, Zhang C, Jia X, Carson DD, Witt R and Farach-Carson MC.  Perlecan domain IV peptide stimulates salivary gland cell assembly in vitro.  Tissue Engineering: Part A. 2009; 15:3309-3320 (Full Text PDF)

Yang M, Adla S, Temburni MK, Patel VP, Lagow EL, Brady OA, Tian J, Boulos MI, Galileo DS. Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule. Cancer Cell Int. 2009. 29;9:27. (Full Text PDF)



Cooper, CR, Graves, B, Pruitt, F, Chaib, H, Lynch, JE, Cox, AK, Sequeria, L, van Golen, KL, Evans, A, Czymmek, K, Bullard, RS, Donald, CD, Sol-Church, K, Gendernalik, JD, Weksler, B, Farach-Carson, MC, Macoska, JA, Sikes, RA, and Pienta, KJ.  Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-α. J Cellular Biochemistry. 2008. 104: 2298–2309

Brown AJ, Alicknavitch M, D'Souza SS, Daikoku T, Kirn-Safran CB, Marchetti D, Carson DD, Farach-Carson MC. Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone. 2008. 43(4):689-699. (Full Text PDF)

Griffiths GS, Galileo DS, Reese K, and Martin-DeLeon PA. Investigating the role of murine epididymosomes and uterosomes in GPI-linked protein transfer to sperm using SPAM1 as a model. Molucular Reproduction and Development. 2008. 75:1627-1636. (Full Text PDF)

Wagner RC and Hossler FE.  Tomographic Modeling of Casted Blood Vascular Systems.  inFocus Magazine. (11) 2008. (Full Text PDF)


Barwe SP, Maul RS, Christiansen JJ, Anilkumar G, Cooper CR, Kohn DB, Rajasekaran AK. Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix. (Int J Oncol. 2007 Apr;30(4):899-904.)  


Deeble PD, Cox ME, Frierson HF, Sikes RA, Palmer JB, Davidson RJ, Casarez EV, Amorino GP, Parsons SJ. Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells. (Cancer Res. 2007 Apr 15;67(8):3663-72.)  


Degraff DJ, Malik M, Chen Q, Miyako K, Rejto L, Aguiar AA, Bancroft DR, Cohen P, Sikes RA. Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model. (J Cell Physiol. 2007 May 10;). 


Kendall J, Kendall C, Ali-Khan Catts Z, Radford C, Dasch K. Using adult learning theory concepts to address barriers to cancer genetic risk assessment in the african american community. (J Genet Couns. 2007 Jun;16(3):279-88.) 


Kirn-Safran CB, Oristian DS, Focht RJ, Parker SG, Vivian JL and Carson DD. Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29. Developmental Dynamics. 2007. 236:447-460. 


O'connor JC, Farach-Carson MC, Schneider CJ, Carson DD. Coculture with Prostate Cancer Cells Alters Endoglin Expression and Attenuates Transforming Growth Factor-{beta} Signaling in Reactive Bone Marrow Stromal Cells. (Mol Cancer Res. 2007 Jun;5(6):585-603.) 


O'dwyer PJ, Eckhardt SG, Haller DG, Tepper J, Ahnen D, Hamilton S, Benson AB, Rothenberg M, Petrelli N, Lenz HJ, Diasio R, DuBois R, Sargent D, Sloan J, Johnson CD, Comis RL, O'Connell MJ Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups. (J Clin Oncol. 2007 Jun 1;25(16):2313-21.) 


Sun, Y-X,  Fang M, Wang J, Cooper CR, Pienta KJ, and Taichman RS. Expression and Activation of avb3 Integrins by SDF-1/CXC12 Increases the Aggressiveness of Prostate Cancer Cells (The Prostate 67: 61-73). (2007). 




Adla S, Temburni MK, Patel VP, Yang M, Lagow E, Cretu A, Tian J, Kudish P, Galileo DS. Stimulation of glioma and breast cancer cell motility by proteolysis and release of the L1 neural cell recognition molecule (AACRP, Apr 2006). 


Chen Q, Watson JT, Marengo SR, Decker KS, Coleman I, Nelson PS, Sikes RA. Gene expression in the LNCaP human prostate cancer progression model: Progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo (Cancer Lett. 2006 Feb 21;).  


Cretu, A, Fotos JS, Little BW, and Galileo DS. Human and rat glioma growth, invasion, and vascularization in a novel chick embryo brain tumor model (Clin Exper Metas, 22, 225-236).  (2005).


Datta MW, Schlicht MJ,DeGueme AM, Kahler AJ, Hernandez AM, Barrett, A Datta S, Dhir R, Shah RB, Farach-Carson C. Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway (Molecular Cancer 2006, 5:9). 


Huang WC, Wu D, Xie Z, Zhau HE, Nomura T, Zayzafoon M, Pohl J, Hsieh CL, Weitzmann MN, Farach-Carson MC, Chung LW. 2-Microglobulin Is a Signaling and Growth-Promoting Factor for Human Prostate Cancer Bone Metastasis (Cancer Res. 2006 Sep 15;66(18):9108-16).  


Muir C, Chung LW, Carson DD, Farach-Carson MC. Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells. (Clin Exp Metastasis. 2006;23(1):75-86). 


Ogunnaike, BA. Elucidating the digital control mechanism for DNA damage repair with the p53–Mdm2 system: single cell data analysis and ensemble modelling (J. Roy. Soc. Interface. 3, 175-184, 2006).



Mayawala K, Vlachos DG and Edwards JS. Computational modeling reveals molecular details of epidermal growth factor binding (BioMed Central Cell Biology Research Article, Nov 2005).


McLane MA, Zhang X, Tian J, Zelinskas C, Srivastava A, Hensley B, Paquette-Straub C, Scratching below the Surface: Wound Healing and Alanine Mutagenesis Provide Unique Insights into Interactions between Eristostatin, Platelets and Melanoma Cells (2005). 


Yamaguchi N, Chae B-S, Zhang L, Kiick KL, and Furst EM. Rheological Characterization of Polysaccharide-Poly(ethylene glycol) Star Copolymer Hydrogels (Biomacromolecules 2005, 6, 1931-1940).


Yamaguchi N and Kiick KL. A Polysaccharide-Poly(ethylene glycol) Star Copolymer as a Scaffold for the Production of Bioactive Hydrogels (Biomacromolecules 2005, 6, 1921-1930).



Copyright © 2011 CTCR Core Facility | | Newark DE 19716