The Center for Translational Cancer Research

Kirk J. Czymmek, Ph.D.

Associate Professor, Director Center for Translational Cancer Research Core Facility

University of Delaware
Department of Biological Sciences
Wolf Hall, Room 309
Newark, DE 19716

Phone Number: 
(302) 831-3450

Ph.D., Michigan State University: 1993
B.S., State University of New York - Oswego: 1989

 

Research Interests:

Dr. Czymmek’s lab is interested in using contemporary molecular cytology, preparation, and imaging technologies to understand aspects of fungal cell biology, namely-plant pathogenic interactions and mechanisms of fungal hyphal tip growth. Model systems include the rice pathogen Magnaporthe grisea, which is the causal agent of rice blast disease and is of worldwide economic importance, and Phytophthora phaseoli, which is the causal agent of downy mildew in lima bean a very important processing crop in the Delmarva Peninsula.

Currently, Dr. Czymmek’s lab, in collaboration with DuPont Ag Biotech, is utilizing spectral variants of green fluorescent protein (GFP) tagged fungal hyphae and four-dimensional imaging techniques to visualize entire host-pathogen encounter sites in planta, over time. In addition, the lab is involved with in vivo time-course imaging of the effect of fungicides on specific fungal structures and organelles with specific fusion proteins.