The Center for Translational Cancer Research

Kelvin H. Lee, Ph.D.

Director, Delaware Biotechnology Institute, Gore Professor Department of Chemical Engineering

Delaware Biotechnology Institute
Delaware Technology Park
15 Innovation Way
Newark DE 19711

Phone Number: 
(302) 831-0344
Fax: 
(302) 831-48

Ph.D., California Institute of Technology, 1995
M.S., California Institute of Technology, 1993
B.S., Princeton University 1991

 

Research Interests:
With the right tools, one can identify the genetic basis for many different phenotypes or disease states. Our research laboratory is focused on the development of next generation tools for protein  expression profiling and the use of existing tools applied to specific problems in biomolecular engineering and medicine. Our current areas of focus include: 1) the use of proteomics in support of a passive immunization clinical trial for the treatment of Alzheimer's disease; 2) the study of enhanced heterologous protein secretion in bacterial and mammalian cells including a detailed understanding of protein translation; and 3) the development of nanoscale materials and technologies for protein separation. We rely heavily on computational methods as well as biological mass spectrometry and we actively pursue both gel-based as well as shotgun-based proteomics approaches.